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Rhapsody Tonic
Appetite Stimulant With Multivitamines And Calcium
Bottle of 200ml
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Rhapsody Tonic
Appetite Stimulant With Multivitamines And Calcium
COMPOSITION :
Each 15 ml contains:
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Cyproheptadin HCL (Anhydrous) |
BP |
2mg |
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Vitamin A |
BP |
2500I.U |
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Vitamin D3 |
BP |
300I.U. |
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Thiamine HCL |
BP |
5mg |
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Ribloflavin |
BP |
2.5mg |
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Pyridoxine HCl |
BP |
1.5mg |
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Cyanocobalamin |
BP |
5mg |
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Ascorbic Acid |
BP |
45mg |
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D-Panthenol |
USP |
10mg |
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Niacinamide |
BP |
25mg |
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Calcium Lactate
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BP |
100mg |
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Flavoured Syrup base q.s. |
Overages of Vitamins added to compensate loss on storage.
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CLINICAL PHARMACOLOGY:
(1) Pharmacodynamics :
Cyproheptadine is serotonin and histamine antagonist with anticholinergic and sedative
effects. Antiserotonin and antihistamine drugs appear to comglasse with serotonin
and histamine, respectively, for receptor sites. Multivitamin preparation specially
designed to ensure a valuable Micronutrient supply.
Vitamins are essential nutrients. They are indispensable for the normal development
and growth of the foetus and the infant, for the metabolism and formation of carbohydrates,
energy, lipids, nucleic acids and proteins, as well as for the synthesis of amino
acids, collagen and neurotransmitters. Calcium is necessary for healthy bones and
teeth.
Pharmacokinetics:
After a single 4 mg oral dose of 14C-labeled cyproheptadine HCl in normal subjects,
given as tablets or syrup, 2-
20% of the radioactivity was excreted in the stools. Only about 34% of the stool
radioactivity was unchanged drug,
corresponding to less than 5.7% of the dose. At least 40% of the administered radioactivity
was excreted in the urine. No significant difference in the mean urinary excretion
exists between the tablet and syrup formulations. No detectable amounts of unchanged
drug were present in the urine of patients on chronic 12-20 mg daily doses of cyproheptadine
syrup. The principle metabolite found in human urine has been identified as a quaternary
ammonium glucuronide conjugate of cyproheptadine. Elimination is diminished in renal
insufficiency.
Indications :
Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis
due to inhalant allergens and foods, Mild, uncomplicated allergic skin manifestations
of urticaria and angioedema. Amelioration of allergic reactions to blood or plasma
Cold urticaria Dermatographism.
As therapy for anaphylactic reactions adjunctive to epinephrine and other standard
measures after the acute manifestations have been controlled.
This combination vitamin/mineral product is used to prevent or treat nutritional
deficiency caused by certain stressful health conditions (e.g., infections, stomach/intestinal
disorders, various vitamin deficiency syndromes, anorexia, deficiency caused by
certain medications).
Nutritional disorders caused by inadequate diet, anorexia, pregnancy & lactation.
Before & after operation Convalescence. To treat deficiency states of multiple vitamins
as per indications mentioned above.
Contraindications:
Rhapsody Tonic should not be used by patients with pre-existing hypervitaminosis
D or with impaired renal function, iron accumulation and iron utilisation disorders,
hypercalcaemia or hypercalciuria, and hypersensitivity to any ingredient of the
product.
Precautions
Adverse Reactions
Adverse reactions which have been reported with use of antihistamines are as follows:
Central Nervous System: Sedation and sleepiness (often transient), dizziness, disturbed
coordination, confusion, restlessness, excitation,
Miscellaneous: Fatigue, chills, headache, increased apglassite/weight gain.
Dosage and Administration:
Adult: 1 Tablespoon full(15ml) Twice in a day.
Childeren: As directed by physiscian
Overdosage:
In the event of overdosage occurring, An emetic should be administered as soon as
possible, followed by gastric lavage if indicated. Immediately following emesis,
a large dose of a saline cathartic should be used to speed passage through the intestinal
tract.
Presentation:
1 X 200ml Bottle
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